Downloading ARIA

We provide the most recent as well as past versions of ARIA for download. For more information on system requirements, and on how to install ARIA, please follow the instructions given in the Installation notes. Please also have a look at Documentation the which provides a manual, examples, and a tutorial.

If you use the software, please cite the following reference(s):

1. Rieping W., Habeck M., Bardiaux B., Bernard A., Malliavin T.E., Nilges M. (2007) ARIA2: automated NOE assignment and data integration in NMR structure calculation Bioinformatics 23:381-382 Pubmed

Important: Please note that versions 2.0 to 2.3.2 are not compatible with CNS 1.3

Beta grid version 2.3

The source code of Grid version 2.3 is available as a tarball: ariagrid2.3.tar.gz

• Grid version 2.3 is based on the ARIA software library.

• Grid version 2.3 is an extension of the version 2.3 of the program. It offers several new features:

• run ARIA on a grid with a glite middleware.
• use Prosa2003 for the analysis.

The latest version (2.3.2)

The source code of version 2.3 is available as a tarball: aria2.3.tar.gz

• Version 2.3.2 updates version 2.31 and  offers several new features:

• compatibility with CCPNmr Analsyis 2.4
• new PDF reports
• improved Zinc ions patches
• Constraints combination
• Automatic superimposition of best structures and bundle RMSD
• Adaptive violation tolerance (cf Mareuil et al. J Bio NMR 015)
• various fixes
  

• ARIA version 2.3 requires the python module numpy (Numeric not supported)

Past versions

Version 2.3.1

The source code of version 2.3 is available as a tarball: aria2.3.tar.gz

• Version 2.3 is based on the ARIA software library.

• Version 2.3 is an extension of the version 2.2 of the program. It offers several new features:

• extension of support for symmetric oligomers (C3, C5 and D2 symmetries)
• compatibility with CCPNmr version 2 (version 1 not supported)
• improved import/export of CCPN data (eg. import of structure models, NMR Calculation runs in Analysis...)
• introduction of a log-harmonic potential for distance restraints (Nilges et al. Structure, 2008)
• support for coordinated zinc ions
• automated Molprobilty clashlist analysis
• partial support for solid-state NMR through CCPN Distance constraint lists (see Note)

• ARIA version 2.3 requires the python module numpy (Numeric not supported)

NB : The log-harmonic potential requires to recompile CNS with the sources provided in the aria archive (See README or installation notes)

Version 2.2

The source code of version 2.2 is available as a tarball: aria2.2.tar.gz

• Version 2.2 is based on the ARIA software library. The modular design of the library makes it easy for the user to extend and modify the program.

• Version 2.2 is an extension of the version 2.1 of the program. It offers several new features:

• Calculation of symmetric homo-dimers
• Spin-diffusion correction with relaxation matrix calculation
• Network-anchoring analysis
• GUI enhancements (addition of a visual tool to analyse ARIA assignments)
• CCPN support improvement (import of restraints list)
• Graphical outputs (network-anchoring, RMS violation, WHATIF scores profiles)

• ARIA version 2.2 now supports the numpy package as a replacement for Numeric.

Version 2.1

The source code of version 2.1 is available as a tarball: aria2.1.tar.gz

• Version 2.1 is based on the ARIA 2 software library, which has been introduced with version 2.0 of the program. The modular design of the library makes it easy for the user to extend and modify the program.

• A new graphical user interface (GUI) replaces the html-based input form of version 1.x. The GUI enables one to modify all relevant program parameters, such as the iterative protocol and the simulated annealing schedule, the shape of the restraining potentials, as well as names and locations of the data files.

• ARIA now fully supports the CCPN data model to enable spectroscopists to use existing NMR computer programs in an efficient way. For example, a calculation can be launched directly from a CCPN project, and ARIA exports the result of a calculation, mainly the assigned peak lists, restraint lists, and the structure ensembles, to the CCPN project. The incorporation of the CCPN data model has the further advantage, that users can employ the CCPN FormatConverter for importing more than 20 proprietry data formats into CCPN.

Version 2.0

A tarball containing the source code of version 2.0 is available here: aria2.0a.tar.gz

• Version 2.0 is a complete rewrite of version 1.x. It comes in the form of an open software library written in the object-oriented programming language Python.

• Version 2.0 also introduces a new XML data format to represent input data such as the molecular system, and shift and peak lists.

• Furthermore, a graphical user interface replaces the web-based input form of earlier versions of the prorgam.

Version 1.x

Version 1.x of ARIA is no longer supported.